Spurs are looking to win three consecutive top-flight meetings with Manchester United for the first time since September 1960.
Manchester United have lost their last three away Premier League matches against Spurs – they had lost just three of their first 23 against them in the competition between 1992 and 2014 (W12 D8).
Spurs could become the first team since Everton in 1987 to win four consecutive home top-flight matches against Manchester United.
Manchester United have lost two of their last three matches at Wembley in all competitions (including this exact fixture last season), as many as they had in their last 15 at the ground (W8 D5 L2).
Manchester United have won just four of their last 17 away Premier League matches in London (D4 L9).
After winning their last four league games against fellow ‘big six’ opposition last season, Manchester United are winless in their five such matches this term (D2 L3).
Victory here would see Ole Gunnar Solskjaer equal Matt Busby’s record of a Manchester United manager winning their first five league games in charge of the club.
Harry Kane and Lucas Moura (2) were on the scoresheet in Tottenham’s 3-0 win in the reverse fixture – only Clint Dempsey in 2012-13 and Jermaine Jenas in 2005-06 have scored home and away against Man Utd for Spurs in the same Premier League campaign.
Tottenham’s Harry Kane has scored eight goals in his last eight Premier League starts.
For club and country in all competitions, Manchester United’s Alexis Sanchez has been directly involved in nine goals in his nine appearances at Wembley Stadium, scoring eight and assisting one.
Marcus Rashford has been directly involved in nine goals in his last eight Premier League games for Manchester United (4 goals, 5 assists), and is looking to score in three consecutive top-flight games for the first time in his career.
Have something to tell us about this article?