Wolves beat Tottenham 3-1 at Wembley in December 2018 and can win back-to-back away league games against them for the first time.
Last season’s victory is Wolves’ only triumph in seven league games against Spurs (D2, L4).
Tottenham can claim three consecutive home league victories for the first time since winning their first three top-flight games at their new stadium in April 2019.
Spurs have kept only three clean sheets in 22 matches in all competitions under Jose Mourinho.
They could suffer three consecutive league and cup defeats for the first time this season. It would also be their 400th home loss in the top flight.
Lucas Moura has gone 10 Premier League appearances without a goal since scoring in December’s 2-1 win at Wolves.
Dele Alli is one short of becoming the seventh player to score 50 Premier League goals for Spurs.
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Wolves are unbeaten in their eight Premier League games in London (W3, D5) since promotion in 2018 – their longest undefeated top-flight run in the capital since an 11-match sequence between 1972 and 1974.
Nuno Espirito Santo’s side have kept three consecutive clean sheets in the Premier League, as many as they had in their previous 23 games in the competition.
They have conceded just one goal in the last six league games Willy Boly has played in (scored by Southampton’s Danny Ings on 3 October).
Defeat would be Wolves’ 100th in the Premier League.
Raul Jimenez has scored 12 goals in 27 Premier League games this season, just one fewer than he managed in 38 matches last term.
Matt Doherty could make his 250th league appearance for Wolves.
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